Genetic Associations and Epidemiology

31 works in the bibliography carry this topic. Each used an Axivity accelerometer to collect data, or evaluated one as an instrument.

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2026

  1. Accelerometer-Measured Moderate-to-Vigorous Physical Activity and Cancer Risk: Dose–Response from Observational and Nonlinear Mendelian Randomization in UK Biobank (opens in new tab)
  2. Different Intensities of Physical Activity Substituted for Sedentary Time and Risk of Type 2 Diabetes: Integration of Genetics and Wearable Data. (opens in new tab)

2025

  1. Accelerometer-Derived Rest-Activity Rhythm Amplitude, Genetic Predisposition, and the Risk of Ischemic Heart Disease: Observational and Mendelian Randomization Study (opens in new tab)
  2. Circulating Cytokines Mediate the Protective Effect of Physical Activity on Cardiovascular Diseases: A Mendelian Randomization Mediation Analysis (opens in new tab)
  3. Genome-wide association analysis of composite sleep health scores in 413,904 individuals (opens in new tab)
  4. Genome-Wide Association Study Identifies Genetic Loci Involved with Sleep Fragmentation

  5. Physical Activities and Parkinson's Disease Progression: A Two‐Sample Mendelian Randomization Study (opens in new tab)

2024

  1. Association between physical activity and sedentary behavior and gestational diabetes mellitus: a Mendelian randomization analysis (opens in new tab)
  2. Causal association of physical activity with lymphoma risk: a Mendelian randomization analysis (opens in new tab)
  3. Causal inference between physical activity and chronic diseases: Insights from a two-sample Mendelian randomization study (opens in new tab)
  4. Physical activity, sedentary behavior, and risk of sepsis: a two-sample mendelian randomization study (opens in new tab)
  5. The relationship between accelerometer-based physical activity, sedentary behavior, and seven common geriatric syndromes: a two-sample Mendelian randomization study (opens in new tab)

2023

  1. Accelerometer-measured intensity-specific physical activity, genetic risk and incident type 2 diabetes: a prospective cohort study (opens in new tab)
  2. Associations of polygenic inheritance of physical activity with aerobic fitness, cardiometabolic risk factors and diseases: the HUNT study (opens in new tab)
  3. Causal effects of physical activity on the risk of overall ovarian cancer: A Mendelian randomization study (opens in new tab)
  4. Physical Activity, Sedentary Behavior, and Osteoarthritis: A Two-Sample Mendelian Randomization Analysis (opens in new tab)

2022

  1. Association of Sedentary and Physical Activity Behaviors with Body Composition: a Genome-Wide Association and Mendelian Randomization Study (opens in new tab)
  2. Association of sedentary and physical activity behaviours with body composition: a genome-wide association and Mendelian randomisation study (opens in new tab)
  3. Physical activity, sedentary behavior, and the risk of type 2 diabetes: A two-sample Mendelian Randomization analysis in the European population (opens in new tab)

2021

  1. Physical Activity and Risks of Cardiovascular Diseases: A Mendelian Randomization Study (opens in new tab)
  2. Physical activity, sedentary behavior and risk of coronary artery disease, myocardial infarction and ischemic stroke: a two-sample Mendelian randomization study (opens in new tab)
  3. Polygenic score for physical activity provides odds for multiple common diseases (opens in new tab)

2020

  1. Association of physical activity and sedentary behavior with type 2 diabetes and glycemic traits: a two-sample Mendelian randomization study (opens in new tab)
  2. Polygenic Risk Scores and Physical Activity (opens in new tab)

2019

  1. Effect of communicating phenotypic and genetic risk of coronary heart disease alongside web-based lifestyle advice: the INFORM Randomised Controlled Trial (opens in new tab)
  2. Genetic studies of accelerometer-based sleep measures yield new insights into human sleep behaviour (opens in new tab)
  3. Physical activity and risk of lung cancer: a two-sample Mendelian randomization study (opens in new tab)

2018

  1. Biological Insights Into Muscular Strength: Genetic Findings in the UK Biobank (opens in new tab)
  2. Genome-Wide Association Study of Circadian Rhythmicity in 71,500 UK Biobank Participants and Polygenic Association with Mood Instability (opens in new tab)

2017

  1. Fitness, Physical Activity, and Cardiovascular Disease: Longitudinal and Genetic Analyses in the UK Biobank Study (opens in new tab)
  2. Genome-wide association study of habitual physical activity in over 277,000 UK Biobank participants identifies multiple variants including <i>CADM2</i> and <i>APOE</i> (opens in new tab)